TBI – Survivors, Caregivers, Family, and Friends

Posts tagged ‘David Figurski’

Read All About It! . . . . . . . Prisoners without Bars: A Caregiver’s Tale

Read All About It!

Prisoners without Bars: A Caregiver’s Tale

presented by 

Donna O’Donnell Figurski – author

Donna & David with ARC of Prisoners without Bars: A Caregiver’s Tale

My memoir, Prisoners without Bars: A Caregiver’s Tale, is not only a story of David’s and my struggles after his traumatic brain injury, but it is also a love story. Though my memoir addresses a dire topic, it is peppered with comedic situations. They say laughter is the best medicine, and again, they are right.

Prisoners without Bars is a heart-wrenching memoir that will make you laugh, cry, and G-A-S-P. I promise!

Boy Laughing

Girl Crying girl-crying-clipart-34

Girl Gasping 2

It’s not a beach read, but it reads like one. It’s fast! It’s easy! It’s fascineasy. I mean fascinating.

What Readers are Saying!

Jackie said – “A beautiful and touching story.”

Anonymous Amazon Customer said – “I loved this book. almost couldn’t put it down.

jlgwriter said – “I found the story powerful and compelling.

Todd & Kim said – “This is such an inspirational story of survival! The book is a very easy read and informative as well as inspiring!!”

Judy said – “Donna O’Donnell Figurski tells her story of grace, love, frustration, anger, disappointment, strength, joy, and above all hope.”

Marge said – “I read it in one fell swoop… I guess the word that would describe your book, your life, and who you are is SUPERCALIFRAGILISTICEXPIALIDOCIOIUS.”

Anonymous said – “This book pulled me in immediately and didn’t let me go until the end! ”

Helen said – “Could not put this book down. Written for easy reading. It was like having a conversation with a friend.” “I finished it in one day with some teary moments along with some chuckles. A must read!!”

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Stay Safe and Healthy!

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COVID-19: Vaccines (Part 2 of 3): Protection by Antibodies is Only Part of the Story

COVID-19: Vaccines (Part 2 of 3): Protection by Antibodies is Only Part of the Story
by
Columbia University Professor Emeritus, Dr. David Figurski
presented by
Donna O’Donnell Figurski

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 and the disease it causes as COVID-19.  Because the majority of people, including much of the press, commonly refer to the virus as “COVID-19,” to avoid confusion, I use COVID-19 as the name of the virus.)

 

David H. Figurski, Ph.D & Survivor of Brain Injury

Vaccination against COVID-19 primes your immune system to be ready to use every defense it has to fight the virus. It stimulates the creation of a potent and specific defense tailored to fight the COVID-19 virus.

Vaccination has been shown to be amazingly effective. All three vaccines for COVID-19 that have been used in the US (Moderna, Pfizer, and Johnson & Johnson) are 100% effective in preventing both hospitalization and death.

When people think of vaccination, they usually think only of antibodies. But this ignores the stimulation of an equally potent arm of immune system.

The bottom line is that vaccination (1) stimulates the production of antibodies that bind to the virus to prevent infection and (2) creates and activates “killer” T cells that destroy cells that have been infected.

Because antibodies are only part of the defensive power of your immune system, no one should be worried about variants, despite hysterical articles by a largely ignorant press.  We should certainly continue to monitor variants, but there is nothing to be worried about yet.  The antibodies are less able to block virus, but they still work.  Importantly, the killer T cells are unaffected by any variant.

The T cell response after vaccination against COVID-19 is as potent as the antibody arm of the immune system.  Some people cannot make antibodies, yet they do well after infection by COVID-19.

Some facts:

Your immune system is composed of two parts.  A first line of defense (Innate Immunity) acts immediately against any foreign substance.  It is non-specific.  After about a week, a specific and more potent immunity (Adaptive Immunity) has developed. The adaptive arm uses antibodies and T cells.

Vaccination stimulates your adaptive immunity, so the antibodies and T cells are ready before infection.

Scientists don’t yet know how long the anti-COVID-19 antibody levels remain high, but data show that antibodies have remained high for six months so far.  You may need to get vaccinated every year, as you do for the flu virus.

The antibody level will eventually go down, but your immune system maintains a few “memory cells” of the antibody-producing cells. These cells make antibody-producing cells immediately after infection.  So your immune system is fully armed in 2-3 days.

I strongly urge you to listen to minutes 6:25-22:00 of the interview TWiV 736 <March 28, 2021>of Dr. Alessandro Sette, a world-renowned expert on T cells and COVID-19 from The La Jolla Institute for Immunology, by Dr. Vincent Racaniello, a virologist and expert on COVID-19 from Columbia U.  Dr. Sette gives a basic explanation of T cells, the response to COVID-19, and vaccination.

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COVID-19: Dr. Fauci: Don’t Worry – Santa Claus – Immune to COVID-19

COVID-19: Dr. Fauci: Don’t Worry – Santa Claus – Immune to COVID-19
by
Columbia University Professor Emeritus, Dr. David Figurski
presented by
Donna O’Donnell Figurski

 

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 and the disease it causes as COVID-19. Because the majority of people, including much of the press, commonly refer to the virus as “COVID-19,” to avoid confusion, I use COVID-19 as the name of the virus in this post.)

David H. Figurski, Ph.D & Survivor of Brain Injury

     Children and parents don’t have to worry that the pandemic will ruin Christmas.

 Dr. Anthony Fauci, a member of the President’s Coronavirus Task Force and Director of the National Institute of Allergy and Infectious Diseases, has stated (video) that Santa has excellent innate immunity. (Innate immunity is the body’s first line of defense against viruses. Specific neutralizing antibodies develop a couple of days later.)

 Santa’s immunity is so good that he can’t get infected by COVID-19 and, consequently, he can’t spread the virus. In fact, he doesn’t need a vaccine. All the elves and Mrs. Claus are staying safe by wearing masks and practicing social distancing. It also turns out that the cells of Santa’s reindeer don’t make the receptor for the virus, so the reindeer can’t be infected.santa-2

 

For those who are concerned about receiving gifts on Christmas morning, the good news is that Santa and his reindeer will make their usual Christmas eve worldwide trip.

To track Santa’s trip around the world on December 24th, 2020, go to Norad Tracks Santa.

Have a safe and healthy Merry Christmas

(Clip Art compliments of Bing.)

(Photos compliments of contributor.)

 

Prisoners without Bars: A Caregiver’s Tale

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COVID-19: The President’s Infection (Part 4 of 4)

COVID-19: The President’s Infection (Part 4 of 4)

by

Columbia University Professor Emeritus, Dr. David Figurski

presented by

Donna O’Donnell Figurski

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 and the disease it causes as COVID-19. Because the majority of people, including much of the press, commonly refer to the virus as “COVID-19,” to avoid confusion I use COVID-19 as the name of the virus in this post.)

David H. Figurski, Ph.D & Survivor of Brain Injury

The President returned to the White House Monday evening. Was that too soon? Was the President at risk? Was he contagious?

The President’s doctors at Walter Reed were comfortable with his leaving the hospital because the White House has its own doctors and medical facility. Remdesivir is given IV for five days. Putting in an IV line would not be a problem at the White House. If the President needed supplemental oxygen, a chest X-ray, antibiotics, etc., they are readily available. The doctors at the White House can also do the daily blood tests needed to monitor the state of the President’s immune system and his propensity for clotting. Dexamethasone is usually prescribed for ten days, but an oral form is available.

Two important questions loomed. Is the President immune? And, is the President contagious?

The conferral of immunity by COVID-19 infection is a major question yet to be answered. If there is protective immunity and, if so, how long it lasts are major concerns of vaccine producers. There are now reports of people being infected with COVID-19 a second time. Immunity may depend on the severity of the initial infection and the robustness of the consequent immune response. There has been a report of mild or asymptomatic infections that do not elicit an antibody response. Are these people more vulnerable to a second infection? Alternatively, was their response so effective without antibodies that the virus could not become established and cause symptoms?

Is the President contagious? We can’t say without knowing his test results. Dr. Griffin considers a patient virus-free if that person has two negative tests on two consecutive days. Otherwise, a person is considered to be potentially contagious for 20 days. Since the doctors are permitting the President to hold rallies, I assume he is not thought to be contagious.

Dr. Griffin’s extensive experience with COVID-19 patients has allowed us to surmise what was happening with the President’s infection. The President appears to have completely recovered from his COVID-19 infection. But, several questions remain.

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Prisoners without Bars: A Caregiver’s Tale

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COVID-19: The President’s Infection (Part 2 of 4)

COVID-19: The President’s Infection (Part 2 of 4)

by

Columbia University Professor Emeritus, Dr. David Figurski

presented by

Donna O’Donnell Figurski

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 and the disease it causes as COVID-19. Because the majority of people, including much of the press, commonly refer to the virus as “COVID-19,” to avoid confusion I use COVID-19 as the name of the virus in this post.)

David H. Figurski, Ph.D & Survivor of Brain Injury

Dr. Griffin labels Week 1 of the infection as the “viral phase.” During Week 1, the virus is multiplying and is present in abundance. A test for COVID-19 would easily be positive. Because the President first felt symptoms on Wednesday, it’s likely that the President was infected for several days before the positive result on Friday, October 2.

Other data suggest that the President was at the end of Week 1 of the infection or at the beginning Week 2.

Week 2 of the infection is called the “cytokine storm phase” by Dr. Griffin.Cytokine Cytokines are molecules released by some cells that cause an action by other cells. When certain immune system cells sense a problem (like a virus-infected cell), they release cytokines to get other immune cells to multiply, to make attack molecules, or to come and help eliminate the cause of the problem. Normally, the immune system works well, but sometimes the immune system overreacts and causes severe problems or even death. “Cytokine storm” refers to an overreaction by the immune system. A steroid (for example, dexamethasone, which the President was given) is effective because it will dampen the immune response, a potentially beneficial effect when the immune system is overreacting. But, dexamethasone is considered harmful if the drug is not needed. (For example, dexamethasone is not given in Week 1 <the viral phase> because a normally functioning immune system is needed to reduce the amount of virus in the body.)

The President began taking dexamethasone while he was at Walter Reed. Dr. Griffin said that dexamethasone is not usually given in Week 1 because studies have shown that doing so can make COVID-19-disease outcomes worse. National Institutes of Health guidelines for physicians state that dexamethasone should only be given to patients with moderately severe or serious COVID-19 disease. The White House acknowledged that the President received oxygen before he was taken to Walter Reed. Supplemental oxygen is consistent with the President’s being given dexamethasone. Dr. Griffin said that oxygen, if needed, is usually given in Week 2, further indicating that the President’s infection may have started several days before Friday. October 2nd.

Doctors have found that COVID-19 has a third phase – a “clotting phase,” which starts at the end of Week 2 and extends at least through Week 3. COVID-19 infection can trigger clots, which can sometimes (albeit rarely) lead to strokes. Aspirin is routinely given at the end of Week 2 because it helps prevent clotting. Some patients had already been discharged from the hospital (having had two negative COVID-19 tests over two consecutive days and having agreed to self-quarantine for 14 days as a precaution) when a problem-clot occurred.

(To Be Continued)

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Prisoners without Bars: A Caregiver’s Tale

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COVID-19: Love in the Time of a Pandemic

COVID-19: Love in the Time of a Pandemic

by

Columbia University Professor Emeritus, Dr. David Figurski

presented by

Donna O’Donnell Figurski

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 and the disease it causes as COVID-19.  Because the majority of people, including much of the press, commonly refer to the virus as “COVID-19,” to avoid confusion I use COVID-19 as the name of the virus in these posts.)

David H. Figurski, Ph.D & Survivor of Brain Injury

Donna and I recently celebrated 51 years of marriage.  We chose the beautiful desert scenery around the White Tank Mountains near our home in Arizona.  We returned to the place that Donna proposed to me last year as part of our 50th anniversary celebration.

This year, our anniversary celebration was very different.  We are in the middle of a global pandemic of a new coronavirus.  To slow the spread of this highly contagious virus, most people wear masks, practice social-distancing, and self-quarantine.  (For us, except for monthly food pick-up runs, we have been home over 160 days.)

Desert near the White Tank Mountains

The effect of the pandemic has been horrific and devastating for society, most notably for health-care personnel, blue-collar workers, teachers and school administrators, and middle- and lower-class families, who are struggling with paying bills, having enough food, and eviction.

Donna & David Figurski Wedding Anniversary #51

Globally, there have been over 22.5 million confirmed cases of COVID-19, and over 795,000 people have died. The U.S. has over 5.5 million cases and over 175,000 deaths. Scientists and physicians around the world are racing to understand the virus and its disease.  A viable vaccine is months away.

David & Donna Figurski – so happy together

Everyone is trying to cope as best as he or she can. On a personal level, Donna and I are fortunate to deeply love one another and to have each other in the midst of such chaos.

Love is worth celebrating wherever and whenever you can.

Stay Safe and Healthy!

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COVID-19 – It’s Everywhere . . Will an Early Vaccine for COVID-19 Be Safe?


Will an Early Vaccine for COVID-19 Be Safe?

by

Columbia University Professor Emeritus, Dr. David Figurski

presented by

Donna O’Donnell Figurski

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 and the disease it causes as COVID-19. Because the majority of people, including much of the press, commonly refer to the virus as “COVID-19,” to avoid confusion I use COVID-19 as the name of the virus in these posts.)

 

David Figurski

David H. Figurski, Ph.D & Survivor of Brain Injury

There is intense pressure from this Administration for any good news that might bolster its re-election chances. The government’s own FDA (Food and Drug Administration) might shorten the three required clinical trials that are key to proving the safety and efficacy of any vaccine before it’s approved for use by the public.

There is good reason to be concerned that government officials from this Administration might approve short-cuts to well-established scientific requirements because they want to speed things up. Both the FDA and the CDC (Centers for Disease Control & Prevention), two government agencies I have always trusted, have already bowed to political pressure from this Administration. The FDA approved hydroxychloroquine use for COVID-19 and later rescinded its approval when the drug was found to be ineffective against COVID-19 and to cause some dangerous side-effects in some people. The CDC, after feeling pressure from the Administration, revamped its back-to-school guidelines.

twiv-300x225

Dr. Vincent Racaniello – Columbia University virologist

Drs. Vincent Racaniello (virologist, Columbia U., host of the TWiV <This Week in Virology> podcasts), Brianne Barker (immunologist, Drew U.), and Rich Condit (retired virologist, Professor Emeritus, U. of Florida) discuss this issue in the TWiV podcast #631 of June 25, 2020. I urge you to listen to minutes 4:00-9:00. These three scientists talk about the importance of impartial and uncorrupted science in driving vaccine development and approval.

Also, an article about this issue can be found in the July 29, 2020, issue of HuffPost.

VaccineA legitimate way for the large Phase III clinical trial to end early is when the benefit is obvious. For example, if a vaccine candidate were given to 20,000 people and a placebo were given to another 20,000 people, the efficacy of the vaccine would be obvious (and statistically sound) if several hundred people in the placebo group became sick, while no person in the vaccine group became sick. Such an obvious result is exceedingly rare, and so, since it normally takes about eight months to do a Phase III clinical trial, if all goes well, we probably won’t have a confidence-inspiring vaccine until 2021.

Stay Safe and Healthy!

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COVID-19 — It’s Everywhere . . . Vaccine is Possible

COVID-19 . . . Evidence that a Vaccine is Possible

by

Columbia University Professor Emeritus, Dr. David Figurski

presented by

Donna O’Donnell Figurski

 

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 and the disease it causes as COVID-19.  Because the majority of people, including much of the press, commonly refer to the virus as “COVID-19,” to avoid confusion, I use COVID-19 as the name of the virus in these posts.)

COVID-19

The 100+ labs trying to develop a vaccine for COVID-19 were delighted with a study showing that COVID-19 stimulates a strong antibody response in humans. Scientists from the University of California at San Diego (UCSD) demonstrated that a vaccine for COVID-19 is definitely possible.

The scientists studied blood from mildly sick individuals who recovered. They found a high level of antibodies to the spike protein, used by COVID-19 to infect.

The strong antibody response suggests that immunity will occur in humans and will last a while, but no one knows for how long – weeks? months? years?

The scientists were surprised by another result. For you also to understand it, I have to give you some background. (Sorry!)

There are seven coronaviruses that infect humans.

Four are common and cause mild, cold-like symptoms.  We’ve all probably had one or more of these.

Three coronaviruses (SARS-CoV, SARS-CoV-2 <which causes COVID-19>, and MERS- CoV) cause serious human disease and some fatalities.

Blood taken before COVID-19 even existed in humans nevertheless showed the presence of antibodies that reacted with COVID-19.  Infection with one of the mild coronaviruses may have stimulated the body’s production of some antibodies that cross-react with COVID-19.

Some seemingly healthy individuals have died from COVID-19. In contrast, some people not predicted to do well had mild disease or were asymptomatic. Doctors are perplexed by their inability to predict who will recover.

David H. Figurski, Ph.D & Survivor of Brain Injury

One possibility is that the amount of cross-reactive antibodies arising from previous infection with one or more of the mild coronaviruses may determine how well a COVID-19-infected person will do.

 

Stay Safe and Healthy!

 

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COVID-19 — It’s Everywhere . . . To Open or Not to Open

COVID-19 . . . To Open or Not to Open

by

Columbia University Professor Emeritus, Dr. David Figurski

presented by

Donna O’Donnell Figurski

 

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 and the disease it causes as COVID-19.  Because the majority of people, including much of the press, commonly refer to the virus as “COVID-19,” to avoid confusion, I use COVID-19 as the name of the virus in these posts.)

COVID-19

David H. Figurski, PhD — Brain Injury Survivor — Professor Emeritus of Microbiology & Immunology — Columbia University

 

Some governors say “Open.” Scientists say “Don’t open.” Whom do you believe?

I’m a scientist.  I know where I stand.

Below are some facts to help you decide.

For those of you in the west, the coronavirus infections have just begun.  You can see from the map of May 19 (see below) that infections are still moving westward.

Coronavirus Map – New York Times – 05/19/20

Many people, particularly those in the west, don’t seem to understand that the US is still in the early stages of this pandemic. They are lulled by the low number of cases in their state. The numbers are misleading for two reasons.

(1) Only seriously symptomatic (mostly hospitalized) people and celebrities are being tested because the US is seriously in need of more testing.  (2) The virus has not reached you yet. (That’s the especially true in the western half of the US.)

New York City is still very bad, but strict social-distancing guidelines have produced a significant drop in new cases.

Washington State had the potential to become a major hot spot, but they acted quickly and aggressively.

In contrast, several states are opening up and relaxing guidelines, despite a continued rise in new cases.  (That’s the case here in Arizona, where Governor Ducey allowed restaurants to open this week. This decision is particularly horrifying because the pandemic hasn’t really reached us yet.)

Reported cases in the United States

(Every red dot represents a cluster of infections – probably started by an infected asymptomatic traveler.  Right now, most cases are in the east, but every day you see more red dots in the western half of the US.)

 

David H. Figurski, Ph.D & Survivor of Brain Injury

Stay Safe and Healthy!

 

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On the Air: . . . . . . . . . . . . . . . Guest: Dr. David Figurski

On the Air: Guest: Dr. David Figurski

presented by

Donna O’Donnell Figurski

David Figurski

David H. Figurski, Ph.D & Survivor of Brain Injury

 

Dr. David Figurski, retired professor of microbiology, talks about his brain injury and COVID-19

I don’t often publicize my radio show on the Brain Injury Radio Network, but one of our brain injury survivors is knowledgeable about the COVID-19 pandemic, which I’m sure is on your mind.  Like me, you probably have lots of questions.

My guest on the April 19th show was my husband, Dr. David Figurski.  David has been living with several physical disabilities since January 2005, when he had a brain hemorrhage, but, fortunately, after three brain surgeries in two weeks, he was unaffected cognitively.  For 35 years, including eight years after his traumatic brain injury, David was a professor in the Department of Microbiology & Immunology at Columbia University, where he also had a research lab.  David has done research on bacteria and viruses for 45 years.  Unsurprisingly, he has been very interested in the new human coronavirus and the global pandemic it has caused.news-clipart-news-anchor-4

My 80-minute show was live on April 19th, but it was recorded and can now be listened to at any time as a podcast.  My interview of David has two parts.  From 9:30 to 49:50, David and I talk about life with his brain injury.  From 49:50 to the end, David and I discuss the COVID-19 pandemic.

To Listen Go To:

SPEAK OUT! On the Air with . . . Brain Injury Radio Show Menu “Another Fork in the Road”

blogtalkradio.com/braininjuryradio/2020/04/20/another-fork-in-the-road-bi-survivorcolumbia-prof-dr-david-figurski-covid19

 

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