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Long COVID . . . . . . . . . . . . . . Serious Long-term Effect of Some COVID-19 Infections

Long COVID – a Serious Long-term Effect of Some COVID-19 Infections


by


Columbia University Professor Emeritus, Dr. David Figurski

presented by

Donna O’Donnell Figurski

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 <severe acute respiratory syndrome coronavirus #2> and the disease it causes as COVID-19 <coronavirus infectious disease of 2019>.  Because the majority of people, including most of the press, commonly refer to the virus as “COVID-19” or “COVID,” to avoid confusion, I use “COVID-19” as the name of the virus.)

David Figurski

David H. Figurski, Ph.D & Survivor of Brain Injury

Finally – the news I’ve been waiting for!

Bottom line: The news is good … if you’re vaccinated.

Dr. Daniel Griffin, a Columbia University infectious disease physician, has said that long COVID is a public health crisis.  Several million people worldwide are living with the mysterious, often disabling, ailments of long COVID.

What is long COVID?

Everybody knows about the acute phase of COVID-19 infection. Some infections are serious and require hospitalization – and maybe intensive care. However, infected people and even the survivors of hospitalization seem to fully recover. They feel fine and test negative for the virus.coronavirus_PNG38

But weeks or months later, people who appear to have recovered from a COVID-19 infection may experience any one or several symptoms, which include fatigue, severe headaches, brain fog, anxiety, depression, muscle pain, cough, fever, cognitive impairment, joint pain, chest pain, shortness of breath, vertigo or loss of balance, memory issues, rash, heart palpitations, and sleep issues.

What’s worse – the symptoms can persist. No one knows when the symptoms will end. Some long COVID patients worry that their symptoms will be lifelong. Society needs to be ready for many more disabled people.

Scientists and doctors don’t know the cause.

Particularly worrisome is the fact that even asymptomatic and mild infections can lead to long COVID. Since vaccination still permits asymptomatic and mild infections but prevents the severe infections that require hospitalization, I have been concerned that long COVID can still occur with vaccination. Now it’s clear that vaccination prevents long COVID too.

Because long COVID occurs weeks or months after a COVID-19 infection, it took a while for the data on vaccination and long COVID to come out.

apps.31154.13510798883188545.eeff598f-9fb6-4eae-b36b-53296e4adb2eA recent paper submitted by an Israeli group showed there is a significant reduction (an appropriately conservative conclusion for data that showed 0 cases of long COVID) if a person was vaccinated before getting infected.  In contrast, with no vaccination, about half of hospitalized COVID-19 patients will get long COVID. Vaccination after getting COVID-19 helps: Vaccination within 30 days of COVID-19 infection helps reduce the incidence of long COVID significantly. Getting vaccinated 30-60 days after COVID-19 infection helped, but not as much as within 30 days. Getting vaccinated after 90 days post COVID-19 infection does not help.

You can listen to Dr. Griffin talk about long COVID in two short segments – minutes 38:25-41:30 and 47:25-50:15 – of his clinical update in the video podcast (TWiV #856 – This Week in Virology by Columbia virologist Dr. Racaniello.

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COVID-19 – It’s Everywhere . . Will an Early Vaccine for COVID-19 Be Safe?


Will an Early Vaccine for COVID-19 Be Safe?

by

Columbia University Professor Emeritus, Dr. David Figurski

presented by

Donna O’Donnell Figurski

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 and the disease it causes as COVID-19. Because the majority of people, including much of the press, commonly refer to the virus as “COVID-19,” to avoid confusion I use COVID-19 as the name of the virus in these posts.)

 

David Figurski

David H. Figurski, Ph.D & Survivor of Brain Injury

There is intense pressure from this Administration for any good news that might bolster its re-election chances. The government’s own FDA (Food and Drug Administration) might shorten the three required clinical trials that are key to proving the safety and efficacy of any vaccine before it’s approved for use by the public.

There is good reason to be concerned that government officials from this Administration might approve short-cuts to well-established scientific requirements because they want to speed things up. Both the FDA and the CDC (Centers for Disease Control & Prevention), two government agencies I have always trusted, have already bowed to political pressure from this Administration. The FDA approved hydroxychloroquine use for COVID-19 and later rescinded its approval when the drug was found to be ineffective against COVID-19 and to cause some dangerous side-effects in some people. The CDC, after feeling pressure from the Administration, revamped its back-to-school guidelines.

twiv-300x225

Dr. Vincent Racaniello – Columbia University virologist

Drs. Vincent Racaniello (virologist, Columbia U., host of the TWiV <This Week in Virology> podcasts), Brianne Barker (immunologist, Drew U.), and Rich Condit (retired virologist, Professor Emeritus, U. of Florida) discuss this issue in the TWiV podcast #631 of June 25, 2020. I urge you to listen to minutes 4:00-9:00. These three scientists talk about the importance of impartial and uncorrupted science in driving vaccine development and approval.

Also, an article about this issue can be found in the July 29, 2020, issue of HuffPost.

VaccineA legitimate way for the large Phase III clinical trial to end early is when the benefit is obvious. For example, if a vaccine candidate were given to 20,000 people and a placebo were given to another 20,000 people, the efficacy of the vaccine would be obvious (and statistically sound) if several hundred people in the placebo group became sick, while no person in the vaccine group became sick. Such an obvious result is exceedingly rare, and so, since it normally takes about eight months to do a Phase III clinical trial, if all goes well, we probably won’t have a confidence-inspiring vaccine until 2021.

Stay Safe and Healthy!

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