TBI – Survivors, Caregivers, Family, and Friends

Archive for June 18, 2020

COVID-19 — It’s Everywhere . . . Drug Breakthrough Significantly Prevents COVID-19 Deaths

Drug Breakthrough Significantly Prevents COVID-19 Deaths

by

Columbia University Professor Emeritus, Dr. David Figurski

presented by

Donna O’Donnell Figurski

 

(Disclaimer: The World Health Organization <WHO> has officially named the new coronavirus as SARS-CoV-2 and the disease it causes as COVID-19. Because the majority of people, including much of the press, commonly refer to the virus as “COVID-19,” to avoid confusion I use COVID-19 as the name of the virus in these posts.)

COVID-19

David H. Figurski, Ph.D & Survivor of Brain Injury

Research at the University of Oxford in England showed for the first time that a drug prevented a major fraction of deaths in severely sick patients with COVID-19.

Dexamethasone was found in a large clinical trial to cause a significant reduction in deaths. It can be prescribed as pills, and it is a common, readily available, and relatively inexpensive drug

A major problem after infection by COVID-19 is that the immune response of some individuals is too aggressive (often causing what’s called a “cytokine storm”) and can lead to death. Because dexamethasone is a steroid that dampens the immune response, the prediction was that it might help to prevent deaths by COVID-19.

The research showed that it does.

There are about 3 deaths for every 8 patients on ventilators.  Dexamethasone treatment reduced those deaths by one-third.  So, 1 death would be prevented for every 8 patients on ventilators.  About 5 deaths occur in every 25 patients on oxygen only. Dexamethasone treatment reduced those deaths by one-fifth, or about 1 less death for every 25 patients on oxygen only. Dexamethasone treatment had no effect on patients not on ventilators or receiving oxygen only.

Given that a major fraction of the over 118,000 deaths in the US so far (at 6:00 pm ET on June 18, 2020) were on ventilators or oxygen only, dexamethasone treatment is predicted to prevent many deaths.

The UK’s Chief Scientific Adviser, Sir Patrick Vallance, said: “This is a ground-breaking development in our fight against the disease, and the speed at which researchers have progressed finding an effective treatment is truly remarkable.”

 

Stay Safe and Healthy!

Clip Art compliments of Bing.)

(Photos compliments of contributor.)

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